128525-51-9

Upstream product

• 464-48-2 (1S)-camphor 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 196306-65-7 C₃₇H₄₄O₆ 
• 196302-92-8 1D-5-O-allyl-2,6-di-O-benzyl-3-O-endo,4-O-exo-(L-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196306-65-7 1D-2,4,5-tri-O-benzyl-1-O-endo,6-O-exo-(D-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196302-90-6 1D-2,5,6-tri-O-benzyl-3-O-endo,4-O-exo-(L-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196306-65-7 1D-2,4,5-tri-O-benzyl-1-O-exo,6-O-endo-(L-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196306-65-7 1D-2,5,6-tri-O-benzyl-3-O-exo,4-O-endo-(L-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 136774-02-2 C₃₀H₃₉O₉P 
• 136774-02-2 [1R-(1α,2α,4α)-2,3-O-(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]-hept-2-ylidene]-1-[bis(phenylmethyl)phosphate]-myo-inositol 
• 196302-93-9 1D-5-O-allyl-2,6-di-O-benzyl-1-O-(4'-methoxybenzyl)-3-O-endo,4-O-exo-(L-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 
• 196302-94-0 1D-5-O-allyl-2,4-di-O-benzyl-1-O-endo,6-O-exo-(D-1',7',7'-trimethylbicyclo<2.2.1>hept-2'-ylidene)-myo-inositol 

Relevant academic research and scientific papers

SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY OF THE INFLAMMATORY RESPONSE

The present invention relates to novel synthetic analogues of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.

Efficient routes to glucosamine-myo-inositol derivatives, key building blocks in the synthesis of glycosylphosphatidylinositol anchor substances

Short synthetic routes to protected derivatives of 2-amino-2-deoxy-α-D-glucopyranosyl-(1→6)-D-myo-inositol are described. Various 2-azido-2-deoxy-glucosyl donors were synthesized, starting from D-glucal or glucosamine hydrochloride. Derivatives of 1,2- and 2,3- D-myo-inositol-camphanylidene acetals were prepared to function as glycosyl acceptors. The subsequent glycosylations produced useful building blocks for the synthesis of GPI-anchor substances.

5-[2-(2-Methoxy)bornyl]tetrazole as catalyst for dlastereoselective synthesis of 2′-deoxydlnucleoside (3′, 5′)-methylphosphonates

The synthesis of 5-[2-(2-methoxy)bornyl]tetrazole 1 is described. 1 is used as catalyst for the diastereoselective synthesis of some 2′-deoxy dinucleoside (3′, 5′)methylphosphonates in solution. Copyright 1997 by Marcel Dekker, Inc.