1285494-91-8Relevant academic research and scientific papers
Microwave assisted metal-/oxidant-free cascade electrophilic sulfenylation/5-endo-dig cyclization of 2-alkynylanilines to generate diversified 3-sulfenylindoles
Sharma, Shivani,Pathare, Ramdas S.,Sukanya,Maurya, Antim K.,Goswami, Bhagyashree,Agnihotri, Vijai K.,Sawant, Devesh M.,Pardasani, Ram T.
, p. 3823 - 3826 (2017)
A metal-/oxidant-free sustainable protocol for the synthesis of 3-sulfenylindoles based on electrophilic cyclization of 2-alkynylanilines has been developed under microwave irradiation. Herein, catalytic amount of iodine and stoichiometric amount of sulfonyl hydrazides were employed as catalyst and electrophiles respectively to induce the 5-endo-dig cyclization of 2-alkynylanilines. This strategy allows a wide substrate scope, demonstrates good functional group tolerance, utilizes easily available reagents and overcome multistep synthesis.
Copper-catalyzed chalcogenoamination of 2-alkynylanilines with dichalcogenides for one-step synthesis of 3-sulfenylindoles and 3-selenylindoles
Li, Zhen,Hong, Longcheng,Liu, Ruiting,Shen, Jianzhong,Zhou, Xigeng
supporting information; experimental part, p. 1343 - 1347 (2011/04/15)
The copper-catalyzed chalcogenoamination of 2-alkynylanilines with dichalcogenides has been achieved under mild reaction conditions using the weak base Cs2CO3 in combination with air oxidant, providing a convenient and efficient meth
