1285534-86-2

Upstream product

• 87791-88-6 3′,5′-(1,1,3,3-tetraisopropyl-1,3-disiloxan-1,3-yl)-9-(β-D-ribofuranosyl)purin-2,6-diamine 
• 1285534-90-8 2'-O-[2-(N-methylcarbamoyl)ethyl]-2-N-phenoxyacetyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-aminoadenosine 
• 1285534-89-5 2'-O-[2-(N-methylcarbamoyl)ethyl]-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-aminoadenosine 
• 1285534-85-1 2'-O-[2-(methoxycarbonyl)ethyl]-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-aminoadenosine 

Downstream Products

• 1285534-81-7 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(N-methylcarbamoyl)ethyl]-2-N-phenoxyacetylguanosine 3'-(2-cyanoethyl-N,N-diisopropylphosphoramidite) 
• 1285534-91-9 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(N-methylcarbamoyl)ethyl]-2-N-phenoxyacetylguanosine 

Relevant academic research and scientific papers

Synthesis of 2′-O-[2-(N-methylcarbamoyl)ethyl]ribonucleosides using oxa-michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides

To develop oligonucleotides containing new 2′-O-modified ribonucleosides as nucleic acid drugs, we synthesized three types of ribonucleoside derivatives modified at the 2′-hydroxyl group with 2-(methoxycarbonyl)ethyl (MOCE), 2-(N-methylcarbamoyl)ethyl (MC