Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1285539-32-3

2-ethoxy-5-nitro-N-(2-trifluoromethylphenyl)benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1285539-32-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1285539-32-3 Structure

  • Basic information

    1. Product Name: 2-ethoxy-5-nitro-N-(2-trifluoromethylphenyl)benzamide
    2. Synonyms: 2-ethoxy-5-nitro-N-(2-trifluoromethylphenyl)benzamide
    3. CAS NO:1285539-32-3
    4. Molecular Formula:
    5. Molecular Weight: 354.285
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1285539-32-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-ethoxy-5-nitro-N-(2-trifluoromethylphenyl)benzamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-ethoxy-5-nitro-N-(2-trifluoromethylphenyl)benzamide(1285539-32-3)
    11. EPA Substance Registry System: 2-ethoxy-5-nitro-N-(2-trifluoromethylphenyl)benzamide(1285539-32-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1285539-32-3(Hazardous Substances Data)

1285539-32-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1285539-32-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,5,5,3 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1285539-32:
(9*1)+(8*2)+(7*8)+(6*5)+(5*5)+(4*3)+(3*9)+(2*3)+(1*2)=183
183 % 10 = 3
So 1285539-32-3 is a valid CAS Registry Number.

1285539-32-3Relevant articles and documents

Design and Synthesis of Novel Cyclooxygenase-1 Inhibitors as Analgesics: 5-Amino-2-ethoxy-N-(substituted-phenyl)benzamides

Fukai, Ryosuke,Zheng, Xiaoxia,Motoshima, Kazunori,Tai, Akihiro,Yazama, Futoshi,Kakuta, Hiroki

, p. 550 - 560 (2011/12/22)

We previously found that N-(4-aminophenyl)-4-trifluoromethylbenzamide (TFAP), a COX-1 inhibitor, exhibits an analgesic effect without causing gastric damage. Unfortunately, TFAP causes reddish purple coloration of urine, and its analgesic effect is less potent than that of indomethacin. Herein we describe our study focusing on the development of 4- and 5-amino-2-alkoxy-N-phenylbenzamide scaffolds, designed on the basis of the structures of TFAP and parsalmide, another known COX-1 inhibitory analgesic agent. 5-Amino-2-ethoxy-N-(2- or 3-substituted phenyl)benzamide derivatives exhibited analgesic activity in a murine acetic acid induced writhing test. Among these compounds, 5-amino-2-ethoxy-N-(2-methoxyphenyl)benzamide (9v) possesses potent COX-1 inhibitory and analgesic activities, similar to those of indomethacin. In addition, 5-amino-2-ethoxy-N-(3-trifluoromethylphenyl)benzamide (9g) showed a more potent analgesic effect than indomethacin or 9v without causing apparent gastric damage or coloration of urine, although its COX-1 inhibitory activity was weaker than that of indomethacin or 9v. Thus, 9g and 9v appear to be promising candidates for analgesic agents and are attractive lead compounds for further development of COX-1 inhibitors.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1285539-32-3