1285705-05-6Relevant academic research and scientific papers
Combining Rh-Catalyzed Diazocoupling and Enzymatic Reduction to Efficiently Synthesize Enantioenriched 2-Substituted Succinate Derivatives
Wang, Yajie,Bartlett, Mark J.,Denard, Carl A.,Hartwig, John F.,Zhao, Huimin
, p. 2548 - 2552 (2017)
We report the development of a modular, one-pot, sequential chemoenzymatic system for the formal enantioselective construction of the C-C bond in 2-aryl 1,4-dicarbonyl compounds. This sequence comprises a rhodium-catalyzed diazocoupling that provides >9:1
Rhodium(II)-catalyzed cross-coupling of diazo compounds
Hansen, Joorn H.,Parr, Brendan T.,Pelphrey, Philip,Jin, Quihui,Autschbach, Jochen,Davies, Huw M. L.
supporting information; experimental part, p. 2544 - 2548 (2011/04/27)
Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identifie
