128581-38-4Relevant academic research and scientific papers
Construction of pyrrolophenanthridinone scaffolds mediated by samarium(II) diiodide and access to natural product synthesis
Suzuki, Kenji,Iwasaki, Hiroki,Domasu, Reika,Hitotsuyanagi, Naho,Wakizaka, Yuka,Tominaga, Mao,Kojima, Naoto,Ozeki, Minoru,Yamashita, Masayuki
, p. 5513 - 5519 (2015)
Pyrrolophenanthridinone derivatives including the natural products were readily synthesized by samarium(II)-mediated reductive cyclization of aryl radical onto a benzene ring under mild reaction conditions. This methodology was applied to the concise synt
Regioselectivity in the biaryl coupling reactions of 1-[(1,3-benzodioxol-5-yl)methyl]-7-iodo-2,3-dihydroindole using palladium reagent
Harayama, Takashi,Hori, Akihiro,Abe, Hitoshi,Takeuchi, Yasuo
, p. 385 - 390 (2006)
The biaryl coupling reaction of 1-[(1,3-benzodioxol-5-yl)methyl]-7-iodo-2,3-dihydroindole (1) using Pd(OAc)2 gave selectively 4,5-dihydro-7H-[1,3]dioxolo[4,5-k]pyrrolo[3,2,1-de]phenanthridine (4), which was formed by connection to a more hindered carbon, in 3.4～4.2:1 ratios.
Synthetic studies on pyrrolophenanthridone skeleton from 1-benzoyl-7-iododihydroindole derivatives using palladium-assisted biaryl coupling reactions
Harayama, Takashi,Toko, Hiroko,Hori, Akihiro,Miyagoe, Taeko,Sato, Tomonori,Nishioka, Hiromi,Abe, Hitoshi,Takeuchi, Yasuo
, p. 513 - 520 (2007/10/03)
The biaryl coupling reaction of 1-benzoyl-7-iododihydroindole derivatives using Pd reagent was examined. 1-[(1,3-Benzodioxol-5-yl)carbonyl]-7-iodo-2,3-dihydroindole gave 4,5-dihydro-7H-[1,3]dioxolo[4,5-k]pyrrolo[3,2,1-de] phenanthridin-7-one, which was formed by connection to a more hindered carbon, as a major product. 1-(3,4-Dimethoxybenzoyl)-7-iodo-2,3-dihydroindole gave oxoassoanine and 10,11-dimethoxy-4,5-dihydropyrrolo[3,2,1-de]-phenanthridin-7-one in an almost equal ratio.
A DIRECT SYNTHESIS OF PYRROLOPHENANTHRIDONE ALKALOIDS
Black, David St C.,Keller, Paul A.,Kumar, Naresh
, p. 5807 - 5808 (2007/10/02)
Pyrrolophenanthridone alkaloids were easily synthesized by palladium acetate catalyzed arylation of N-acylindolines (5a-c) followed by dehydrogenation.
