128590-69-2

Upstream product

• 95570-83-5 t-butyl 3-acetoxymethyl-7α-methoxy-3-cephem-4-carboxylate 
• 95570-71-1 t-butyl 3-acetoxymethyl-7α-methoxy-3-cephem-4-carboxylate 1β-oxide 
• 6187-87-7 7-Aminocephalosporanic acid t-butyl ester 
• 95570-73-3 (4R,5S,6R,7S)-3-Acetoxymethyl-7-methoxy-4-methyl-5,8-dioxo-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester 
• 128590-71-6 p-t-butoxycarbonylbenzyl-3-acetoxymethyl-7α-methoxy-2α-methyl-3-cephem-4-carboxylate 
• 95570-72-2 t-butyl 3-acetoxymethyl-7α-methoxy-2-methylene-3-cephem-4-carboxylate 1β-oxide 
• 128658-11-7 (4R,6R,7S)-3-Acetoxymethyl-7-methoxy-4-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester 
• 128590-70-5 (4R,6R,7S)-3-Acetoxymethyl-7-methoxy-4-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 128590-68-1 p-t-butoxycarbonylbenzyl-3-acetoxymethyl-7α-methoxy-2α-methyl-3-cephem-4-carboxylate 1,1-dioxide 

Relevant academic research and scientific papers

Inhibition of human leukocyte elastase by C-2 substituted cephalosporin sulfones

Cephalosporin sulfones with a number of substituents at the C-2 position were prepared and tested as inhibitors of human leukocyte elastase (HLE), an enzyme implicated in the tissue destruction associated with pulmonary emphysema. Nearly all substituents