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Usage

Uses

Used in Pharmaceutical Industry:
(R)-(+)-N-BENZYL-1-PHENYLETHYLAMINE HYDROCHLORIDE is used as a starting material and intermediate in the chemical synthesis of pharmaceutical compounds. Its chiral nature allows for the production of enantiomerically pure drugs, which are crucial for achieving the desired therapeutic effects and minimizing side effects.
Used in the Preparation of (R)-3-Aminobutan-1-ol (A602105):
(R)-(+)-N-BENZYL-1-PHENYLETHYLAMINE HYDROCHLORIDE serves as a starting material for the preparation of (R)-3-Aminobutan-1-ol (A602105), a compound with potential applications in the pharmaceutical industry. This synthesis highlights the versatility of (R)-(+)-N-BENZYL-1-PHENYLETHYLAMINE HYDROCHLORIDE in the development of various pharmaceutical compounds.

InChI:InChI=1/C15H17N.ClH/c1-13(15-10-6-3-7-11-15)16-12-14-8-4-2-5-9-14;/h2-11,13,16H,12H2,1H3;1H/t13-;/m1./s1

Upstream product

• 103-69-5 N-ethyl-N-phenylamine 
• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 

Downstream Products

• 3129-98-4 (R)-benzylidene-(1-phenylethyl)amine 

Relevant academic research and scientific papers

Synthesis of limonene β-amino alcohol from (R)-(+)-α-methylbenzylamine and (+)-limonene 1,2-epoxide

Two new compounds of β-amino alcohol are obtained using (R) - (+) - α-methylbenzylamine as starting material which is converted into two amines. Each of these compounds reacted in excess with a 1: 1 mixture of cis and trans-limonene oxide in the presence of water as a catalyst. The products obtained show that β-amino alcohol derived from trans-limonene oxide is obtained and unreacted cis-limonene oxide from the reaction mixture as well as the amine is attained. Whereas the addition of the synthesized carbamate of the same primary amine over the 1: 1 mixture of cis and trans -limonene oxide in the presence of water results in the hydrolysis product and the recovery of unreacted trans-limonene oxide.

Method of producing optically active cyclopropane derivatives

A method for resolving optically impure 3-oxa-2-oxobicyclo?3.1.0!hexane-1-carboxylic acid esters. A method is provided for producing a 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid.N-benzyl-α-phenylethylamine diastereomer salt. An enantiomer of N-benzyl-α-phenylethylamine is reacted with a 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid to produce a precipitate that is enriched in one diastereomer of the salt. After isolating the optically active salt, the N-benzyl-α-phenylethylamine may be separated to produce the corresponding 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid. Under acidic conditions, the carboxylic acid and hydroxyl groups undergo ring closure to afford the optically active 3-oxa-2-oxobicyclo?3.1.0!hexane-1-carboxylic acid ester.