128596-16-7

Basic information

• Product Name: N-[(2R,3R,4R)-6-(Acetyl-ethyl-amino)-2,4-diphenyl-3,4-dihydro-2H-thiopyran-3-carbothioyl]-N-ethyl-acetamide
• CAS NO: 128596-16-7
• Molecular Weight: 466.668
• Mol File: 128596-16-7.mol

Chemical Properties

• CAS DataBase Reference: N-[(2R,3R,4R)-6-(Acetyl-ethyl-amino)-2,4-diphenyl-3,4-dihydro-2H-thiopyran-3-carbothioyl]-N-ethyl-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2R,3R,4R)-6-(Acetyl-ethyl-amino)-2,4-diphenyl-3,4-dihydro-2H-thiopyran-3-carbothioyl]-N-ethyl-acetamide(128596-16-7)
• EPA Substance Registry System: N-[(2R,3R,4R)-6-(Acetyl-ethyl-amino)-2,4-diphenyl-3,4-dihydro-2H-thiopyran-3-carbothioyl]-N-ethyl-acetamide(128596-16-7)

Safety Data

• Hazardous Substances Data: 128596-16-7(Hazardous Substances Data)

Upstream product

• 27845-85-8 (E)-N-ethyl-3-phenyl-2-propenamide 
• 128596-13-4 N-ethyl-thiocinnamamide 
• 142-29-0 cyclopentene 

Relevant articles and documents

GENERATION AND CYCLOADDITIONS OF 2-(N-ACYLAMINO)-1-THIA-1,3-DIENES. STRUCTURAL INVESTIGATIONS USING NMR METHODS. PART I.

A method has been developed for the efficient generation of 2-(N-acylamino)-1-thia-1,3-dienes.These novel hetero-dienes, which are generated via acylation of the corresponding thioamides, undergo irreversible regio- and stereospecific Diels-Alder addition to the starting thioamides to yield 6-(N-acylamino)-3,4-dihydro-2H-thiopyrans.The regiochemistry, relative configurations and the major solution conformations of the thiopyrans 4a-c and 10 have been determined using NMR techniques.In addition, it has been found that these systems exhibit a number of unique physical and chemical properties.