1286280-89-4Relevant academic research and scientific papers
Microwave-assisted benzyl mono- and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachloride
Pingali, Subramanya R. K.,Upadhyay, Sunil K.,Jursic, Branko S
experimental part, p. 928 - 933 (2011/05/15)
An environmentally friendly benzyl mono- and di-bromination synthetic procedure was developed that is superior to the classic carbon tetrachloride bromination procedure in both reaction time and isolated yield. This new reaction was performed in diethyl carbonate as reaction media using microwave instead of conventional heating. Both the solvent and the brominating reagent N-bromosuccinimide (prepared from succinimide obtained from the reaction mixture) are recyclable. Practically, the preparation of our target compounds was completed in less than two hours. The Royal Society of Chemistry.
Microwave-assisted NBS bromination of p-iminotoluenes: Preparation of new alcohol, mercapto, and amino protection groups
Upadhyay, Sunil K.,Jursic, Branko S.
experimental part, p. 3177 - 3185 (2011/09/20)
A simple, efficient, safe, high-yielding and rapid microwave-assisted method for the preparation of protected p-bromomethyl and p- dibromomethylanilines was developed as new alcohol, thiol, and amine protection groups. The procedure involves microwave-assisted N-bromosuccinimide (NBS) radical bromination of readily available N-protected p-toluidine. The microwave-assisted radical bromination was found to be superior to the conventional NBS radical bromination. Copyright
