128641-86-1

Upstream product

• 128641-85-0 1,5-dimethyl-4-(p-tolylsulfonyl)-3-(trimethylsilyl)pyrazole 
• 128641-89-4 N-methyl-4-(p-tolylsulfonyl)pyrazole 
• 74-88-4 methyl iodide 
• 107696-97-9 3,3-dimethyl-4-(p-tolylsulfonyl)-5-(trimethylsilyl)-3H-pyrazole 

Relevant academic research and scientific papers

A new route to 1,5-disubstituted 4-arylsulfonylpyrazoles by lithiation of 1-methyl-4-arylsulfonylpyrazoles

The arylsulfonylvinamidinium salts 1 reacted with hydrazine in refluxing ethanol to give rise to 4-arylsulfonylpyrazoles 2 in reasonable yield. Regioselective lithiation of N-methylpyrazoles 3 with LDA followed by treatment with various electrophiles affo

Dipolar cycloaddition reaction of diazoalkanes with trimethylsilyl substituted alkynes. Steric control of regiochemistry by the trimethylsilyl group

A study of the cycloaddition behavior of several trimethylsilyl substituted alkynes with 2-diazopropane and diazomethane has been carried out. Aryl or alkyl ethynyl sulfones react to give 5-sulfonyl substituted 3H-pyrazoles which extrude nitrogen on photo