128647-41-6Relevant academic research and scientific papers
Dynamic kinetic resolution of N-benzoyl-DL-amino acids via peptide bond forming reactions
Miyazawa, Toshifumi,Hamada, Takashi
experimental part, p. 419 - 422 (2011/12/04)
Dynamic kinetic resolution (DKR) was demonstrated in the carbodiimide-mediated couplings of N-benzoyl-DL-amino acids with L-amino acid esters: the yields of the D-L-peptides significantly exceeded 50% in some cases. N-benzoyl-DL-t-leucine afforded the D-L-peptide almost exclusively (up to 96% yield) in the reaction with methyl L-prolinate, which is the most efficient DKR obtained in the field of amino acids and derivatives.
