128657-11-4Relevant academic research and scientific papers
Electronic effects of aryl-substituted bis(oxazoline) ligands on the outcome of asymmetric copper-catalysed C-H insertion and aromatic addition reactions
Slattery, Catherine N.,O'Keeffe, Sarah,Maguire, Anita R.
, p. 1265 - 1275 (2013/11/19)
The effect of the modification of bis(oxazoline) ligands on the outcome of copper-catalysed C-H insertion and aromatic addition reactions is described. In general, these reactions display minimum sensitivity in terms of enantiocontrol to variation of the electronic properties of the aryl moiety of the ligand however, some influence is observed for C-H insertions employing naphthyl-substituted bis(oxazolines) and for aromatic addition reactions of biphenyl diazo ketone substrates. The synthesis of the modified bis(oxazolines), which include four novel structures, is also described.
Asymmetric copper-catalysed intramolecular C-H insertion reactions of α-diazo-β-keto sulfones
Slattery, Catherine N.,Maguire, Anita R.
supporting information; experimental part, p. 667 - 669 (2011/03/20)
Asymmetric copper-catalysed intramolecular C-H insertion reactions of a series of α-diazo-β-keto sulfones are reported. Enantioselectivities of up to 82% ee were achieved in moderate to good yield. These results represent the highest level of enantiocontr
Enantioselective introduction of a benzenesulfonylmethyl substituent at an unactivated carbon atom via chemoenzymatic methods
Maguire, Anita R.,Kelleher, Leonard L.
, p. 7459 - 7462 (2007/10/03)
Introduction of a benzenesulfonylmethyl group at the unactivated γ-carbon of carboxylic acid derivatives has been achieved through a combination of rhodium acetate catalysed carbenoid C-H insertion and baker's yeast mediated kinetic resolution. Access to
