1286573-32-7Relevant academic research and scientific papers
Process development and scale-up of AZD7545, a PDK inhibitor
Patel, Bharti,Firkin, Catherine R.,Snape, Evan W.,Jenkin, Shelley L.,Brown, David,Chaffey, Julian G. K.,Hopes, Philip A.,Reens, Carl D.,Butters, Mike,Moseley, Jonathan D.
, p. 447 - 460 (2012)
A brief comparison of the early manufacturing routes to AZD7545 is given. Process development of the preferred long-term manufacturing route is reported in detail, and changes from the initial kilogram-scale route are discussed. Scale-up experience from t
