128669-61-4

Upstream product

• 50547-51-8 3-amino-2-ethylquinazoline-4(3H)-one 
• 128669-59-0 cis-7-(2-ethyl-4-oxoquinazolin-3-yl)-4,4,6-trimethyl-7-azabicyclo<4.1.0>heptan-2-ol 
• 128669-59-0 2-Ethyl-3-(5-hydroxy-1,3,3-trimethyl-7-aza-bicyclo[4.1.0]hept-7-yl)-3H-quinazolin-4-one 
• 470-99-5 isophorol 
• 78-59-1 3,5,5-Trimethylcyclohex-2-en-1-one 
• 128669-60-3 Imidazole-1-carbothioic acid O-[7-(2-ethyl-4-oxo-4H-quinazolin-3-yl)-4,4,6-trimethyl-7-aza-bicyclo[4.1.0]hept-2-yl] ester 
• 128669-60-3 Imidazole-1-carbothioic acid O-[(1R,2S,6R)-7-(2-ethyl-4-oxo-4H-quinazolin-3-yl)-4,4,6-trimethyl-7-aza-bicyclo[4.1.0]hept-2-yl] ester 

Relevant academic research and scientific papers

Pyrrolidines and allylic amines from radical-induced cleavage of aziridines

Cleavage of α-aziridinylalkyl radicals has been observed; the resulting aminyl radicals react with tributyltin hydride to form amines or clyclise onto appropriately sited alkenes to give pyrrolidines.

Regiospecific Radical-induced Cleavage of Aziridines: Syntheses of Allylic Amines and Pyrrolidines

The radical-induced cleavage of a series of fused aziridines has been found to proceed regiospecifically to produce C-N- bond cleavage, and the product radicals afford allylic amines or, in suitable cases, cyclise to form pyrrolidines.