1286838-40-1Relevant academic research and scientific papers
Sequential one-pot reactions of thioformates with lithium silylacetylides, arylmagnesium halides, and electrophiles leading to formation of propargyl sulfides
Murai, Toshiaki,Ohashi, Takayuki,Shibahara, Fumitoshi
, p. 70 - 71 (2011)
One-pot reactions of thioformates with lithium silylacetylides, arylmagnesium halides, and electrophiles that produce propargyl (2-propynyl) sulfides are described. The pathway for this process begins with addition of lithium (trimethylsilyl)acetylide to the thioformate C=S carbon. This step is followed by addition of the arylmagnesium halide to the sulfur atom of the C=S group in the in situ generated propynethial. The intermediacy of the propynethial in this process was confirmed by trapping through a Diels-Alder reaction with cyclopentadiene.
