128691-32-7Relevant academic research and scientific papers
Synthesis of Acenaphthoheterocycles and Spiro
Lefkaditis, D. A.,Nicolaides, D. N.,Papageorgiou, G. K.,Stephanidou-Stephanatou, J.
, p. 227 - 230 (2007/10/02)
Methyl (Z)-(1,2-dihydro-2-oxo-1-acenaphthylenylidene)acetate 1 gives with hydroxylamine the oximes 2 and the pyrrole derivative 4, whereas with hydrazines affords the pyridazinones 5 and 6.A pyridazine derivative 8 is also isolated from the reaction of (1,2-dihydro-2-oxo-1-acenaphthylenylidene)acetone 7 with hydrazine hydrate.Reaction between the spiro-derivative 9 and hydroxylamine hydrochloride gives oxime 10, whereas Wittig olefination of 9 with ylide 11 yields compound 12 which by reaction with 2,4,6-trimethylbenzonitrile oxide (13) affords the dispiro-derivatives 14.Finally from the reaction of acenaphthylene-1,2-quinone (17) with the bisylide 16 the acenaphthothiophene (18) is formed.
