128693-26-5

Upstream product

• 17497-53-9 1-iodo-1-cyclohexene 
• 762-72-1 allyl-trimethyl-silane 
• 17874-17-8 cyclohex-1-enyl-trimethyl-silane 
• 60484-85-7 1-trimethylsilyl-7-oxabicyclo<4.1.0>heptane 
• 128693-16-3 (1R,2R)-2-Trimethylsilanyl-2-((E)-3-trimethylsilanyl-allyl)-cyclohexanol 

Relevant academic research and scientific papers

Regiospecific Synthesis of 1-Silyl Substituted 1,4-Dienes

The reaction of epoxysilanes with lithiated allylsilanes gives predominantly α-silyl-substituted alcohols (3) which are convenient precursors for the preparation of 1-silyl-substituted 1,4-dienes.

Formation of 1-(Trimethylsilyl) 1,4-Dienes by Vinylation of Allyltrimethylsilane in the Presence of the Palladium(0)/Silver Salt System

The major products formed in palladium-catalyzed reactions of allyltrimethylsilane with vinyl iodides, in the presence of silver ion or with vinyl triflates are 1-(tri-methylsilyl) 1,4-dienes.In the absence of silver salts, only traces of these dienes are formed, and desilylation is predominant.Addition of silver salts enhances the reaction rate, suppresses the desilylation, and affects the isomer distribution.The isolated yields of the 1-(trimethylsilyl) 1,4-dienes are, in general, low owing to unfavourable regioselectivity in the reactions.