128705-89-5Relevant academic research and scientific papers
Intracomplex Macrocyclization: a Novel Approach to Effective Synthesis of Cryptands
Lukyanenko, Nikolay G.,Reder, Anatoly S.
, p. 1225 - 1226 (1988)
Dihydroxycryptands are formed in good yield by the reactions of N,N'-bis(oxiranylmethyl)diazacrown ethers with amines.
MACROHETEROCYCLES. 49. SIMPLE SYNTHESIS OF CRYPTANDS BASED ON INTRACOMPLEX MACROCYCLIZATION
Luk'yanenko N. G.,Reder, A. S.
, p. 1394 - 1395 (2007/10/02)
An effective method for synthesizing cryptands by reaction of bis(methylene-epoxy)diazacrown ethers with benzylamine and N,N'-dibenzylethylenediamine is reported.The good yields of cryptands are explained by formation of an intermediate in which the placement of reaction centers is favorable for intramolecular closure due to binding of the macrocycle to substrate.
