128719-99-3Relevant articles and documents
Ring Transformation of 4-Amino-1H-1,5-benzodiazepine-3-carbonitrile with Active Methylene Compounds. A Novel 1,3-Migration of a Cyano Group in 1-Amino-1-(2-aminoanilino)-2,4-dicyano-4-ethoxycarbonyl-1,3-butadiene
Okamoto, Yoshihisa,Zama, Yoshimi,Itoh, Toshihiro,Aotsuka, Tomoji,Kurasawa, Yoshihisa,Takagi, Kaname
, p. 966 - 987 (2007/10/02)
The ring transformation of 4-amino-1H-1,5-benzodiazepine-3-carbonitrile hydrochloride (1) with active methylene compounds are described.The contraction to a pyridine ring ring was readily accomplished by use of DBU as a catalyst.An alternative 1,3-rearran