1287225-52-8

Upstream product

• 124-19-6 nonan-1-al 
• 1287225-45-9 (1R,2S,3S,4R,5R,6S)-2-amino-3,4,5,6-tetrakis(benzyloxy)cyclohexanol 
• 1287225-40-4 (1S,2S,3R,4R,5S,6S)-N-(2,3,4,5-tetrakis(benzyloxy)-6-hydroxycyclohexyl)carbamic acid tert-butyl ester 
• 1198207-03-2 (1S,2S,3S,4R,5R,6S)-2-amino-3,4,5,6-tetrakis(benzyloxy)cyclohexanol 
• 1287225-43-7 (1S,2R,3S,4R,5S,6R)-2,3,4,5-tetrakis(benzyloxy)-6-(tert-butoxycarbonylamino)cyclohexyl methanesulfonate 
• 1287225-44-8 (3aR,4S,5R,6S,7S,7aR)-4,5,6,7-tetrakis(benzyloxy)-hexahydrobenzo[d]oxazol-2(3H)-one 

Downstream Products

• 1287226-85-0 (3aR,4S,5S,6S,7R,7aR)-4-(benzyloxy)-3-nonyl-2-(nonylimino)-octahydrobenzo[d]oxazole-5,6,7-triol 
• 1287226-35-0 N-((3aR,4S,5R,6S,7S,7aR)-4,5,6,7-tetrakis(benzyloxy)-3-nonyl-hexahydrobenzo[d]oxazol-2(3H)-ylidene)nonan-1-amine 
• 1287225-83-5 1,3-dinonyl-1-((1S,2S,3R,4R,5S,6R)-2,3,4,5-tetrakis(benzyloxy)-6-hydroxycyclohexyl)thiourea 

Relevant academic research and scientific papers

Polyhydroxylated bicyclic isoureas and guanidines are potent glucocerebrosidase inhibitors and nanomolar enzyme activity enhancers in gaucher cells

Four diastereomeric series of N-alkylated [6+5] bicyclic isoureas having hydroxyl substituents mimicking glucose hydroxyl groups have been synthesized as potential β-glucocerebrosidase (GCase) inhibitors with the aim of developing pharmacological chaperon