1287287-09-5Relevant articles and documents
Arylation of adamantanamines: III.* Palladium-catalyzed arylation of adamantane-1,3-diyldimethanamine and 2,2′-(adamantane-1,3-diyl) diethanamine
Averin,Ulanovskaya,Buryak,Savel'ev,Orlinson,Novakov,Beletskaya
experimental part, p. 30 - 40 (2011/04/26)
Palladium-catalyzed arylation of adamantane-1,3-diyldimethanamine and 2,2′-(adamantane-1,3-diyl) diethanamine with isomeric bromochloro- and dibromobenzenes was studied. The yields of N,N′-diarylation products depend on the initial diamine and dihalobenzene structure. Side reactions were revealed, which reduced the yield of the target products. The arylation of 2,2′-(adamantane-1,3-diyl)diethanamine gives the corresponding N,N′-diaryl derivatives with better yield. The possibility for synthesizing unsymmetrical N,N′-diaryl derivatives of 2,2′- (adamantane-1,3-diyl)diethanamine was demonstrated.
