128747-06-8

Basic information

• Product Name: trans-methyl 5-cyano-5-phenyl-4,4-dimethyl-pent-2-enoate
• CAS NO: 128747-06-8
• Molecular Weight: 243.305
• Mol File: 128747-06-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: trans-methyl 5-cyano-5-phenyl-4,4-dimethyl-pent-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: trans-methyl 5-cyano-5-phenyl-4,4-dimethyl-pent-2-enoate(128747-06-8)
• EPA Substance Registry System: trans-methyl 5-cyano-5-phenyl-4,4-dimethyl-pent-2-enoate(128747-06-8)

Safety Data

• Hazardous Substances Data: 128747-06-8(Hazardous Substances Data)

Upstream product

• 70335-50-1 methyl (E)-4-bromo-4-methylpenten-2-oate 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

ALLYLIC SUBSTITUTION BY CARBON NUCLEOPHILES ON 4-BROMO-4-METHYL-2-PENTENOATE: ANTI-MICHAEL REGIOSELECTIVITY.

The reaction of carbanions α-to nitriles with tertiary bromoester 1 does not give cyclopropanes, whatever the reaction conditions, while Li enolate of methyl phenylacetate does, in THF or THF-Et2O.From lithiated aminonitriles 5, in THF-HMPA, the reaction leads to a mixture of SN and SN' products in equal amounts via a radical process.From arylaceto- and propionitriles 4 whatever the conditions, and from methyl phenylacetate enolate 16, either associated to Li in THF-HMPA or to K in THF, SN' anti-Michael products are predominantly formed via a concerted inner sphere process, showing thus the possibility of a polar-SET mechanistic spectrum from a single electrophilic reagent.