128767-25-9Relevant academic research and scientific papers
ACETALS OF LACTAMS AND ACID AMIDES. 55. STUDY OF REACTION OF 3-OXOPYRIDINE AND ISOQUINOLIN-3-ONE DERIVATIVES WITH DIMETHYLFORMAMIDE DIETHYL ACETAL
Guss, L. T.,Ershov, L. V.,Bogdanova, G. A.,Granik, V. G.
, p. 183 - 188 (1990)
The reactions of 4-carbamoyl- and 4-cyanopyridin-3-one and 4-cyanoisoquinolin-3-one with DMFA diethyl acetal were studied, and hydrogenated di- and trimethylene derivatives of 2,7-naphthyridine-1,8-dione were synthesized.It was found that O- or N-alkylation reactions of the pyridone fragment of the starting bicyclic compounds take place together with the condensation of the DMFA acetal at the amide amino group or the active methylene unit.
