128775-30-4

Upstream product

• 128775-29-1 methyl 2-O-benzyl-3,5-O-isopropylidene-α-D-lyxofuranoside 
• 87-72-9 D-lyxose 
• 68280-42-2 (4aR,6S,7S,7aR)-6-Methoxy-2,2-dimethyl-tetrahydro-furo[3,2-d][1,3]dioxin-7-ol 
• 22416-73-5 methyl-α-D-lyxofuranoside 

Downstream Products

• 128775-31-5 methyl 2-O-benzyl-5-O-allyl-α-D-lyxofuranoside 
• 128775-37-1 Benzoic acid (2R,3R,4R)-2,3-bis-benzyloxy-5-[(3-benzyloxycarbonylamino-propoxy)-(2-cyano-ethoxy)-phosphoryloxy]-4-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxy)-pentyl ester 
• 128775-39-3 O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-(1-2)-3,4-di-O-benzyl-5-O-benzoyl-D-arabinityl-N,N-diethyl-(2-cyanoethyl)-phosphoramidite 
• 128775-34-8 1-O-allyl-2-O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-3,4-di-O-benzyl-5-O-benzoyl-D-arabinitol 
• 128775-35-9 O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-(1->2)-5-O-benzoyl-3,4-di-O-benzyl-D-arabinitol 
• 128775-33-7 1-O-allyl-3,4-di-O-benzyl-5-O-benzoyl-D-arabinitol 
• 128775-27-9 methyl 2,3-di-O-benzyl-5-O-allyl-α-D-lyxofuranoside 
• 128775-28-0 2,3-di-O-benzyl-5-O-allyl-D-lyxofuranose 
• 128821-27-2 1-O-allyl-3,4-di-O-benzyl-D-arabinitol 

Relevant academic research and scientific papers

Total synthesis of (+)-epiquinamide and (?)-epiepiquinamide from D-mannose

The total synthesis of (+)-epiquinamide and (?)-epiepiquinamide has been achieved starting from a 3,5-dihydroxyfuranoside synthon derived from D-mannose. The methods featured Bernet-Vasella reaction followed by Horner-Wadsworth-Emmons (HWE) reaction to provide a new chiral building block diene as the key steps. The bicyclic framework of this quinolizidine was constructed by using ring-closing metathesis, selective reduction of ester and intramolecular nucleophilic substitution-cyclization.