128778-82-5 Usage
Description
(R)-2,2'-BINAPHTHYL-14-CROWN-4 is a chiral crown ether with a diameter of approximately 1.5 nm. It is a macrocyclic host molecule that can selectively bind to a variety of metal cations and organic guests to form stable complexes. Its unique structure and properties make it a valuable tool in the field of chemical research and applications.
Uses
Used in Asymmetric Synthesis:
(R)-2,2'-BINAPHTHYL-14-CROWN-4 is used as a chiral ligand for enhancing the selectivity and efficiency of asymmetric synthesis reactions. Its ability to selectively bind to metal cations allows for the creation of enantiomerically pure products, which are essential in the pharmaceutical industry and other areas where stereochemistry is critical.
Used in Supramolecular Chemistry:
In the field of supramolecular chemistry, (R)-2,2'-BINAPHTHYL-14-CROWN-4 is used as a host molecule for the formation of stable complexes with various organic guests. This application is crucial for the development of new materials and the study of molecular recognition processes.
Used in Chemical Research:
(R)-2,2'-BINAPHTHYL-14-CROWN-4 serves as a valuable research tool in chemical laboratories. Its unique properties allow scientists to explore new reactions, mechanisms, and interactions between different molecules, contributing to the advancement of chemical knowledge and the development of novel applications.
Used in Analytical Chemistry:
As a chiral selector, (R)-2,2'-BINAPHTHYL-14-CROWN-4 is used in analytical chemistry for the separation and analysis of enantiomers. This is particularly important in the pharmaceutical industry, where the purity and stereochemistry of a compound can significantly impact its efficacy and safety.
Used in Sensor Development:
The selective binding properties of (R)-2,2'-BINAPHTHYL-14-CROWN-4 make it a promising candidate for the development of chemical sensors. These sensors can be used to detect specific metal ions or organic molecules, with potential applications in environmental monitoring, medical diagnostics, and industrial process control.
Check Digit Verification of cas no
The CAS Registry Mumber 128778-82-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,7,7 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 128778-82:
(8*1)+(7*2)+(6*8)+(5*7)+(4*7)+(3*8)+(2*8)+(1*2)=175
175 % 10 = 5
So 128778-82-5 is a valid CAS Registry Number.
128778-82-5Relevant articles and documents
Synthesis, Rapid Resolution, and Determination of Absolute Configuration of Racemic 2,2'-Binaphthyldiyl Crown Ethers and Analogues via β-Cyclodextrin Complexation
Armstrong, Daniel W.,Ward, Timothy J.,Czech, Anna,Czech, Bronislaw P.,Bartsch, Richard A.
, p. 5556 - 5559 (1985)
Twenty racemic and four diastereomeric 2,2'-binaphthyldiyl crown ethers and analogues were synthesized.Chiral interactions between these compounds and immobilized β-cyclodextrin were examined.Thirteen of the enantiomeric pairs and two of the diastereomers were successfully resolved.It was found that relatively small changes in the structure of these compounds could have large effects on chiral recognition.In general, the (-)-S enantiomers formed stronger inclusion complexes with β-cyclodextrin than did the (+)-R enantiomers.
