128779-02-2Relevant academic research and scientific papers
Lithiated 5,6-Dihydro-4H-1,2-oxazines: Synthesis, Highly Diastereoselective Reactions with Electrophiles, and Subsequent Transformations
Reissig, Hans-Ulrich,Hippeli, Claudia
, p. 115 - 127 (2007/10/02)
The 6-(trimethylsilyl)methyl-substituted 1,2-oxazine 1 can smoothly be deprotonated with n-butyllithium at C-4 to give a lithiated species which reacts with a variety of electrophiles to provide the new 1,2-oxazines 5-16 in good yields.Besides the prepara
