1287791-40-5Relevant academic research and scientific papers
INTRAESOPHAGEAL ADMINISTRATION OF TARGETED NITROXIDE AGENTS FOR PROTECTION AGAINST IONIZING IRRADIATION-INDUCED ESOPHAGITIS
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Paragraph 0126; 0141, (2019/07/23)
Provided herein are compositions and related methods useful for prevention or mitigation of ionizing radiation-induced esophagitis. The compositions comprise compounds comprising a nitroxide-containing group attached to a mitochondria-targeting group. The
Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs
Frantz, Marie-Celine,Pierce, Joshua G.,Pierce, Joan M.,Kangying, Li,Qingwei, Wan,Johnson, Matthew,Wipf, Peter
, p. 2318 - 2321 (2011/06/28)
Chemical equations presented. JP4-039 is a novel nitroxide conjugate capable of crossing lipid bilayer membranes and scavenging reactive oxygen species (ROS). An efficient and scalable one-pot hydrozirconation- transmetalation-imine addition methodology h
TARGETED NITROXIDE AGENTS
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Page/Page column 40, (2010/03/02)
Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cro
