1287795-37-2Relevant academic research and scientific papers
Cooperative iron-bronsted acid catalysis: Enantioselective hydrogenation of quinoxalines and 2h-1,4-benzoxazines
Fleischer, Steffen,Zhou, Shaolin,Werkmeister, Svenja,Junge, Kathrin,Beller, Matthias
, p. 4997 - 5003 (2013)
The financial support from the state of Mecklenburg-Vorpommern and the Bundesministerium fur Bildung und Forschung (BMBF) is gratefully acknowledged. S.F. is thankful for the financial support of the Evonik Stiftung. We thank Dr. W. Baumann, Dr. C. Fische
B(C6F5)3-Catalyzed Deoxygenative Reduction of Amides to Amines with Ammonia Borane
Pan, Yixiao,Luo, Zhenli,Han, Jiahong,Xu, Xin,Chen, Changjun,Zhao, Haoqiang,Xu, Lijin,Fan, Qinghua,Xiao, Jianliang
supporting information, p. 2301 - 2308 (2019/01/30)
The first B(C6F5)3-catalyzed deoxygenative reduction of amides into the corresponding amines with readily accessible and stable ammonia borane (AB) as a reducing agent under mild reaction conditions is reported. This metal-free protocol provides facile access to a wide range of structurally diverse amine products in good to excellent yields, and various functional groups including those that are reduction-sensitive were well tolerated. This new method is also applicable to chiral amide substrates without erosion of the enantiomeric purity. The role of BF3 ? OEt2 co-catalyst in this reaction is to activate the amide carbonyl group via the in situ formation of an amide-boron adduct. (Figure presented.).
Dihydrophenanthridine: A new and easily regenerable NAD(P)H model for biomimetic asymmetric hydrogenation
Chen, Qing-An,Gao, Kai,Duan, Ying,Ye, Zhi-Shi,Shi, Lei,Yang, Yan,Zhou, Yong-Gui
supporting information; experimental part, p. 2442 - 2448 (2012/03/10)
A new and easily regenerable NAD(P)H model 9,10-dihydrophenanthridine (DHPD) has been designed for biomimetic asymmetric hydrogenation of imines and aromatic compounds. This reaction features the use of hydrogen gas as terminal reductant for the regenerat
Convergent asymmetric disproportionation reactions: Metal/Bronsted acid relay catalysis for enantioselective reduction of quinoxalines
Chen, Qing-An,Wang, Duo-Sheng,Zhou, Yong-Gui,Duan, Ying,Fan, Hong-Jun,Yang, Yan,Zhang, Zhang
supporting information; experimental part, p. 6126 - 6129 (2011/06/22)
A convergent asymmetric disproportionation of dihydroquinoxalines for the synthesis of chiral tetrahydroquinoxalines using a metal/Bronsted acid relay catalysis system has been developed. The use of hydrogen gas as the reductant makes the convergent dispr
