128786-97-0

Upstream product

• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 128787-04-2 (Z)-2-Methoxy-4-phenyl-2-p-tolyl-but-3-enenitrile 
• 130442-36-3 (Z)-4-Methoxy-2-(4-methylphenyl)-4-phenyl-2-butenenitrile 
• 64686-05-1 3-Methoxy-3-phenyl-2-p-tolyl-propionic acid methyl ester 

Relevant academic research and scientific papers

Thallium in Organic Synthesis. 57. Reaction of Chalcones and Chalcone Ketals with Thallium(III) Trinitrate

Treatment of chalcones (ArCH=CHCOAr') with thallium(III) trinitrate (TTN) in acidic methanol or in trimethyl orthoformate (TMOF) gives 3,3-dimethoxy-1,2-diarylpropan-1-ones (oxythallation, Ar rearrangement) and/or methyl 2,3-diaryl-3-methoxypropanoates (in situ ketal formation, oxythallation, Ar' rearrangement).The effect of substituents on Ar and Ar' on the ratio of the above rearrangement products has been examined.