128787-98-4Relevant academic research and scientific papers
Phase-transfer catalysed alkylation of 4-hydroxycoumarin - Synthesis of α,α-disubstituted o-hydroxyacetophenones
Majumdar,Khan,Chattopadhyay
, p. 483 - 485 (2007/10/02)
Phase-transfer catalysed alkalyation of 4-hydroxycoumarin (1) with active halides give O-alkylated products, 2 (20-60%), C, O-dialkylated products, 3 (15-20%) and α,α-disubstituted-o-hydroxyacetophenones, 5 (20-75%). Only in one case C,C-dialkylated product, 4 (35%) has been obtained.
