128813-27-4

Basic information

• Product Name: Pyridine,2-[(2-propynyloxy)methyl]-(9CI)
• Synonyms: Pyridine,2-[(2-propynyloxy)methyl]-(9CI)
• CAS NO: 128813-27-4
• Molecular Formula: C₉H₉NO
• Molecular Weight: 147.17386
• Product Categories: PYRIDINE
• Mol File: 128813-27-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyridine,2-[(2-propynyloxy)methyl]-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine,2-[(2-propynyloxy)methyl]-(9CI)(128813-27-4)
• EPA Substance Registry System: Pyridine,2-[(2-propynyloxy)methyl]-(9CI)(128813-27-4)

Safety Data

• Hazardous Substances Data: 128813-27-4(Hazardous Substances Data)

Upstream product

• 586-98-1 2-Hydroxymethylpyridine 
• 106-96-7 propargyl bromide 

Downstream Products

• 1422453-88-0 C₁₈H₁₈N₄O₃ 

Relevant articles and documents

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2 - (1 ', 2', 3 '- Triazole - 4' - methyl pyridine oxyalkylene) - 1, 3, 4, 6 - O - acetyl - D - glucose and its preparation method and application

The invention discloses 2-(1',2',3'-triazolyl-4'-oxymethylenepyridyl)-1,3,4,6-O-acetyl-D-glucose with anti-rectal cancer activity. The 2-(1',2',3'-triazolyl-4'-oxymethylenepyridyl)-1,3,4,6-O-acetyl-D-glucose has a core structure of 1,3,4,6-O-acetyl-D-glucose subjected to 1,2,4-triazole derivative 2-site substitution. The above compound has good rectal cancer cell inhibition activity and can be used as a drug for resisting rectal cancer. A compound synthesis method comprises that 2-amino-D-glucose hydrochloride and an azidation reagent as raw materials undergo a reaction under alkaline conditions to produce a 2-azido-1,3,4,6-O-acetyl-D-glucose intermediate, 3-propargyl bromide and aromatic methanol undergo a reaction under the action of sodium hydride to produce aromatic propargyl ether, and the 2-azido-1,3,4,6-O-acetyl-D-glucose intermediate and the aromatic propargyl ether undergo a click reaction in a solvent in the presence of monovalent copper as a catalyst to produce 2-(1', 2', 3'-triazolyl-4'-oxymethylenepyridyl)-1,3,4,6-O-acetyl-D-glucose.