128813-45-6Relevant articles and documents
Development of an Alkyne Analogue of the de Mayo Reaction: Synthesis of Medium-Sized Carbacycles and Cyclohepta[b]indoles
Tymann, David,Tymann, Dina Christina,Bednarzick, Ulf,Iovkova-Berends, Ljuba,Rehbein, Julia,Hiersemann, Martin
, p. 15553 - 15557 (2018)
Embedded medium-sized carbacycles and cyclohepta[b]indoles occur frequently as scaffold elements in natural products and bioactive compounds. Described herein is a conceptionally novel photochemically triggered cascade process to these scaffolds. Key to the cascading ring-expansion process is an unprecedented intramolecular alkyne analogue of the de Mayo reaction.
SYNTHESIS OF SPIROETHERS USING RADICAL CYCLISATIONS
Middleton, Donald S.,Simpkins, Nigel S.,Begley, Michael J.,Terrett, Nicholas K.
, p. 545 - 564 (2007/10/02)
A variety of spiroether products, including one bis-spiro compound, are avaible via a simple radical cyclisation route.