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128831-46-9

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128831-46-9 Usage

Chemical class

Urea class of compounds

Target enzyme

Potent and selective inhibitor of histone deacetylase 6 (HDAC6)

Biological role

Regulation of gene expression, cellular proliferation, and other important biological processes

Potential therapeutic applications

Treatment of various cancers, including multiple myeloma and lymphoma

Mechanism of action

Inhibits the growth and survival of cancerous cells

Additional research areas

Treatment of neurodegenerative diseases and inflammatory conditions

Mode of action in additional research

Modulates the immune response and reduces inflammation

Current status

Interest as a potential therapeutic agent for a variety of conditions

Ongoing activities

Subject of ongoing research and clinical trials

Check Digit Verification of cas no

The CAS Registry Mumber 128831-46-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,8,3 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 128831-46:
(8*1)+(7*2)+(6*8)+(5*8)+(4*3)+(3*1)+(2*4)+(1*6)=139
139 % 10 = 9
So 128831-46-9 is a valid CAS Registry Number.
InChI:InChI=1/C24H18ClF2N3O/c1-13-9-17-21(10-14(13)2)28-12-22(23(17)16-5-3-4-6-18(16)25)30-24(31)29-20-8-7-15(26)11-19(20)27/h3-12H,1-2H3,(H2,29,30,31)

128831-46-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea

1.2 Other means of identification

Product number -
Other names Tmp 153

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:128831-46-9 SDS

128831-46-9Upstream product

128831-46-9Downstream Products

128831-46-9Relevant articles and documents

Quinoline derivatives, their production and use

-

, (2008/06/13)

Quinoline derivatives of the formula: STR1 , wherein R is hydrogen, alkyl or aralkyl; m and n are 0 or 1, and each of rings A, B and C can have substituents, which are useful as inhibitors for acyl-CoA:Cholesterolacyltransferase.

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