128851-55-8

Basic information

• Product Name: 1-[(3-chloro-1-benzofuran-2-yl)sulfonyl]imidazolidine-2,4-dione
• CAS NO: 128851-55-8
• Molecular Formula: C₁₁H₇ClN₂O₅S
• Molecular Weight: 314.7017
• Mol File: 128851-55-8.mol
• Article Data: 1

Chemical Properties

• Density: 1.701g/cm³
• Refractive Index: 1.682
• CAS DataBase Reference: 1-[(3-chloro-1-benzofuran-2-yl)sulfonyl]imidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(3-chloro-1-benzofuran-2-yl)sulfonyl]imidazolidine-2,4-dione(128851-55-8)
• EPA Substance Registry System: 1-[(3-chloro-1-benzofuran-2-yl)sulfonyl]imidazolidine-2,4-dione(128851-55-8)

Safety Data

• Hazardous Substances Data: 128851-55-8(Hazardous Substances Data)

Upstream product

• 128851-72-9 1-(3-chlorobenzo[b]furan-2-ylsulfonyl)-2-thiohydantoin 

Relevant articles and documents

Hydantoin derivatives

The present invention relates to novel hydantoin derivatives, processes for producing said hydantoin derivatives, pharmaceutical compositions containing at least one of said hydantoin derivatives as aldose reductase inhibitors and novel intermediate compounds in the synthesis of said hydantoin derivatives. The present invention is based on the selection of a hydantoin which is bonded by a sulfonyl group to various substituents at the 1-position of the hydantoin skeleton. The compounds of the present invention have a strong inhibitory activity against aldose reductase. These compounds are extremely useful for the treatment and/or prevention of various forms of diabetic complications based on the accumulation of polyol metabolites.