128856-70-2

Upstream product

• 928-97-2 (E)-3-hexen-1-ol 
• 128856-69-9 (2R,3R,5R)-2,3-O-isopropylidene-2,3-dihydroxy-5-(1',3'-E,E-1'-heptadienyl)-cyclohexanone 

Downstream Products

• 128856-71-3 (2R,3R,5R)-2,3-bis-(O-trimethylsilyl)-2,3-dihydroxy-5-(1',3'-E,E-1'-heptadienyl)-cyclohexanone 
• 1166841-83-3 (2R,3R,5R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-5-((1E,3E)-hepta-1,3-dienyl)-cyclohexanone 
• 251959-53-2 (2R,3S,5R,6R)-3-((1E,3E)-Hepta-1,3-dienyl)-2-hydroxymethyl-5,6-bis-trimethylsilanyloxy-cyclohexanone 
• 140224-89-1 3-hepta-1,3-dienyl-5,6-dihydroxy-2-hydroxymethylcyclohexanone 

Relevant academic research and scientific papers

SYNTHESIS OF (+)-PALITANTIN

(-)-Quinic acid was utilized for the synthesis of (+)-palitantin adopting the chiron approach.Pertinent methodology includes stereocontrolled free-radical deoxygenation, functional group adjustments and an α-keto hydroxymethylation reaction.

Asymmetric synthesis of palitantin by an enzymatic and organocatalytic approach

The natural enantiomer of the fungal metabolite (+)-palitantin has been synthesized by adopting a chemoenzymatic and organocatalytic approach. Lipase catalyzed kinetic resolution, Sharpless asymmetric dihydroxylation and organocatalytic asymmetric hydroxy