128899-31-0

Basic information

• Product Name: (+)-D-PYROGLUTAMOL P-TOLUENESULFONATE
• Synonyms: (R)-5-HYDROXYMETHYL-2-PYRROLIDINONE P-TOLUENESULFONATE;(+)-D-PYROGLUTAMOL P-TOLUENESULFONATE;p-Methylbenzenesulfonic Acid (R)-(5-Oxopyrrolidin-2-y l)methyl Ester;p-Methylbenzenesulfonic Acid (R)-(5-Oxopyrrolidin-2-y l)methyl Ester,99%e.e.
• CAS NO: 128899-31-0
• Molecular Formula: C₁₂H₁₅NO₄S
• Molecular Weight: 287.33
• Mol File: 128899-31-0.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (+)-D-PYROGLUTAMOL P-TOLUENESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-D-PYROGLUTAMOL P-TOLUENESULFONATE(128899-31-0)
• EPA Substance Registry System: (+)-D-PYROGLUTAMOL P-TOLUENESULFONATE(128899-31-0)

Safety Data

• Hazardous Substances Data: 128899-31-0(Hazardous Substances Data)

Usage

General Description

"(+)-D-Pyroglutamol p-toluenesulfonate" is a chemical compound. It is an organic molecule, as it contains carbon atoms, and it is a derivative of pyroglutamic acid. The two components in the compound's name, pyroglutamol and p-toluenesulfonate, indicate its structural features. Pyroglutamol refers to a type of amino acid that makes up its molecular structure, and p-toluenesulfonate, also known as tosylate, is a functional group that increases its solubility in organic solvents and can serve as a leaving group in chemical reactions. The "(+)-D" portion of the name indicates that the compound is a chiral molecule, meaning it cannot be superimposed on its mirror image; the "+- D" refers to its specific optical rotation and configuration. (+)-D-PYROGLUTAMOL P-TOLUENESULFONATE could be used for a wide range of applications, including in chemical synthesis, pharmaceuticals, or materials science, due to its structural and chemical properties.

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 4042-36-8 D-pyrrolidone-5-carboxylic acid 
• 68766-96-1 ethyl (R)-2-pyrrolidone-5-carboxylate 
• 64700-65-8 methyl (2R)-pyroglutamate 
• 6893-26-1 D-Glutamic acid 
• 66673-40-3 (R)-5-hydroxymethylpyrrolidin-2-one 

Downstream Products

• 98134-78-2 (R)-2-(5-oxopyrrolidin-2-yl)acetonitrile 
• 808172-50-1 (R)-5-(2-hydroxyethyl)pyrrolidin-2-one 
• 98612-60-3 (5R)-5-(bromomethyl)pyrrolidin-2-one 
• 1431871-14-5 C₂₄H₂₄FN₇O₃ 
• 1431870-94-8 C₂₄H₂₄FN₇O₃ 
• 1431871-17-8 C₂₄H₂₅N₇O₃ 
• 1431871-42-9 C₂₄H₂₃Cl₂N₇O₃ 
• 1005475-16-0 (R)-(1-methyl-5-oxopyrrolidin-2-yl)methyl 4-methylbenzenesulfonate 
• 1431984-95-0 C₂₅H₂₄F₂N₆O₃ 
• 1431984-93-8 C₂₅H₂₅FN₆O₃ 
• 1431985-06-6 C₂₆H₂₇FN₆O₃ 
• 1431984-94-9 C₂₅H₂₆N₆O₃ 
• 63328-11-0 (5R)-5-benzylpyrrolidin-2-one 

Relevant articles and documents

NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE

Described herein are new, selective modulators of the 5 -HT7 receptor. These selective compounds can be useful for the treatment of CNS and non-CNS indications. Compounds described herein can be selective in targeting 5-HT7 receptors

NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE

Pharmaceutical compositions of the invention comprise functionalized lactam derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5- hydroxytryptamine receptor 7 activity. A is selected

MUSCARINIC AGONISTS

This invention relates to compounds that are agonists of the muscarinic M4 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1a or a salt thereof, wherein n, p, Q, R1, R2, R3, R9 and R4 are as defined herein.