1288996-98-4Relevant articles and documents
Pd-catalyzed arylation reactions with phenol diazonium salts: Application in the synthesis of diarylheptanoids
Schmidt, Bernd,Hoelter, Frank,Kelling, Alexandra,Schilde, Uwe
supporting information; experimental part, p. 3357 - 3365 (2011/06/28)
The first total synthesis of the natural product (3S,7R)-5,6-dehydro-de-O- methyl centrolobine and various analogues is reported, using a highly regio- and diastereoselective Mizoroki-Heck reaction of phenol diazonium salts and enantiopure dihydropyrans. The assigned relative configuration was confirmed by single-crystal X-ray structure analysis, but a revision of the absolute configuration is proposed based on polarimetric measurement.