128900-19-6

Basic information

• Product Name: Cyclopenta[b]pyrrole-2-carboxylic acid, octahydro-, (2R,3aR,6aR)- (9CI)
• Synonyms: Cyclopenta[b]pyrrole-2-carboxylic acid, octahydro-, (2R,3aR,6aR)- (9CI)
• CAS NO: 128900-19-6
• Molecular Formula: C₈H₁₃NO₂
• Molecular Weight: 155.19432
• Product Categories: CARBOXYLICACID;PYRROLE
• Mol File: 128900-19-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 304.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.182±0.06 g/cm3(Predicted)
• PKA: 2.47±0.20(Predicted)
• CAS DataBase Reference: Cyclopenta[b]pyrrole-2-carboxylic acid, octahydro-, (2R,3aR,6aR)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopenta[b]pyrrole-2-carboxylic acid, octahydro-, (2R,3aR,6aR)- (9CI)(128900-19-6)
• EPA Substance Registry System: Cyclopenta[b]pyrrole-2-carboxylic acid, octahydro-, (2R,3aR,6aR)- (9CI)(128900-19-6)

Safety Data

• Hazardous Substances Data: 128900-19-6(Hazardous Substances Data)

Upstream product

• 142-29-0 cyclopentene 
• 89226-36-8 N-[(1S,2R)-2-(2-Chloro-2-cyano-ethyl)-cyclopentyl]-acetamide 
• 87623-98-1 (2R,3aS,6aR)-1-Acetyl-octahydro-cyclopenta[b]pyrrole-2-carbonitrile 
• 152972-17-3 (2R,8R,12S)-12-phenyl-1-aza-10-oxatricyclo<6.4.0.0^2,6>dodec-6-en-9-one 
• 147406-85-7 (4R,5aR,8aR,9aR)-4-Phenyl-octahydro-cyclopenta[4,5]pyrrolo[2,1-c][1,4]oxazin-1-one 
• 129101-19-5 (all-R)-2-Azabicyclo[3.3.0]octan-3-oic acid benzyl ester p-toluenesulfonate 

Downstream Products

• 93779-31-8 benzyl (1R^*,3R^*,5R^*)-2-azabicyclo<3.3.0>octane-3-carboxylate 
• 133616-95-2 (1RS,5RS,3'R)-2-Carbamoyl-(3'-methylphenyl)-2-azabicyclo<3.3.0>octan 
• 133696-29-4 (1R,5R)-2-(1-Cyclohexen-1-yl)-2-azabicyclo<3.3.0>octan 
• 156481-92-4 (2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid 
• 156481-90-2 (all-R)-2-(Benzyloxycarbonyl)-2-azabicyclo<3.3.0>octan-3-carbonsaeure-pyrrolidid 
• 156481-94-6 (all-R)-2-(Benzyloxycarbonyl)-2-azabicyclo<3.3.0>octan-3-carboxamid 
• 156481-95-7 (all-R)-2-Azabicyclo<3.3.0>octan-3-carboxamid 
• 478530-92-6 (2R,3aR,6aR)-1-(4-Vinyl-benzyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid methyl ester 
• 478530-85-7 (2R,3aR,6aR)-1-Benzyl-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid methyl ester 
• 125419-12-7 methyl N-methyl-(1SR,3SR,5SR)-2-azabicyclo<3.3.0>octane-3-carboxylate 
• 156557-88-9 (1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid 
• 250370-85-5 (2R,1'R,5'R)-(-)-Benzyl 2-phenyl-2-(2'-azabicyclo[3.3.0]octan-2'-yl)acetate 
• 250370-84-4 (2S,1'R,5'R)-(+)-Benzyl 2-phenyl-2-(2'-azabicyclo[3.3.0]octan-2'-yl)acetate 
• 250371-11-0 (1S,1'R,5'R)-(+)-[2-(2'-Azabicyclo[3.3.0]octan-2'-yl)-1-phenylethyl]thioacetate 

Relevant articles and documents

New Supported β-Amino Alcohols as Efficient Catalysts for the Enantioselective Addition of Diethylzinc to Benzaldehyde under Flow Conditions

(Matrix Presented) Polymeric monoliths 10 containing an amino alcohol moiety derived from an industrial waste material represent one of the best ligands for the enantioselective catalytic addition of ZnEt2 to benzaldehyde (99% ee), being recove

Utilization of Industrial Waste Materials, 1. - Synthesis of New Primary and Secondary Chiral 1,2-Diamines

Primary and secondary 1,2-diamines with three or four stereogenic centers were synthesized starting from the benzyl ester of the bicyclic proline analogue (all-R)-2-azabicyclooctane-3-carboxylic acid by a four- or five-step procedure.This is an example for the utilization of the industrial waste material (all-R)-2b. - Key Words: 1,2-Diamines / 2-Azabicyclooctanes / Proline analogue / Cyclopentapyrroles

Derivatives of bicyclic aminoacids agents containing these compounds and their use

Disclosed are cis, exo- and trans-compounds of the formula I STR1 in which n denotes 0, 1 or 2, R1 denotes hydrogen, (C1 -C6)-alkyl which can optionally be substituted by amino, (C1 -C4)-acyl- or bezoylamino, (C2 -C6)-alkenyl, (C5 -C9)-cycloalkyl, (C5 -C9)-cycloalkenyl, (C5 -C7)-cycloalkyl-(C1 -C4)-alkyl, aryl or partially hydrogenated aryl, which can, in each case, be substituted by (C1 -C2)-alkyl, (C1 -C2)-alkoxy or halogen, aryl-(C1 -C4)-alkyl, /which can be substituted as defined previously in the aryl radical/, a monocyclic or bicyclic sulfur or nitrogen and/or nitrogen heterocyclic radical, or a side chain of naturally occurring aminoacid, R2 denotes hydrogen, (C1 -C6)-alkyl, (C2 -C6)-alkenyl or aryl-(C1 -C4)-alkyl, Y denotes hydrogen or hydroxyl, Z denotes hydrogen or Y and Z together denote oxygen, X denotes (C1 -C6)-alkyl, (C2 -C6)-alkenyl, (C6 -C9)-cycloalkyl or aryl which can be mono-, di- or tri- substituted by (C1 -C4)-alkyl, (C1 -C4)-alkoxy, hydroxyl, halogen, nitro, amino, (C1 -C4)-alkylamino, di-(C1 -C4 -alkylamino or methylenedioxy, or indol-3-yl, or physiologically acceptable salts thereof, a process of the preparation thereof, agents containing them, their use as a medicine and intermediates for the preparation thereof.