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1289132-07-5

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1289132-07-5 Usage

General Description

4-Bromo-2-isobutoxypyridine is a chemical compound with the molecular formula C10H14BrNO. It is a pyridine derivative with a bromo substitution at the 4-position and an isobutoxy group attached to the 2-position. 4-broMo-2-isobutoxypyridine is commonly used as a building block in organic synthesis and pharmaceutical research. It is known for its role as a versatile intermediate in the production of various organic compounds and pharmaceuticals. Its unique structure and reactivity make it a valuable tool for the creation of diverse chemical compounds with potential applications in pharmaceuticals, agrochemicals, and materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 1289132-07-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,9,1,3 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1289132-07:
(9*1)+(8*2)+(7*8)+(6*9)+(5*1)+(4*3)+(3*2)+(2*0)+(1*7)=165
165 % 10 = 5
So 1289132-07-5 is a valid CAS Registry Number.

1289132-07-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-2-(2-methylpropoxy)pyridine

1.2 Other means of identification

Product number -
Other names 4-bromo-2-isobutoxypyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1289132-07-5 SDS

1289132-07-5Upstream product

1289132-07-5Downstream Products

1289132-07-5Relevant articles and documents

Ligand Specific Efficiency (LSE) Index for PET Tracer Optimization

Auberson, Yves P.,Briard, Emmanuelle,Sykes, David,Reilly, John,Healy, Mark

, p. 1415 - 1427 (2016)

Ligand efficiency indices are widely used to guide chemical optimization in drug discovery, due to their predictive value in the early steps of optimization. At later stages, however, as more complex properties become critical for success, indices relying on calculated, rather than experimental, parameters become less informative. This problem is particularly acute when developing positron emission tomography (PET) imaging agents, for which nonspecific binding (NSB) to membranes and non-target proteins is a frequent cause of failure. NSB cannot be predicted using in silico parameters. To address this gap, we explored the use of the experimentally determined chromatographic hydrophobicity index on immobilized artificial membranes, CHI(IAM), to guide the optimization of NSB. The ligand specific efficiency (LSE) index was defined as the ratio between affinity (pIC50or pKd) and the logarithmic value of CHI(IAM). It allows for quantification of binding affinity to the target of interest, relative to NSB. Its use was illustrated by the optimization of PET tracer candidates for the prostacyclin receptor.

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