128917-47-5Relevant academic research and scientific papers
N-heterocyclic carbene (NHC)-catalyzed direct amidation of aldehydes with nitroso compounds
Fong, Tian Wong,Patra, Pranab K.,Seayad, Jayasree,Zhang, Yugen,Ying, Jackie Y.
supporting information; experimental part, p. 2333 - 2336 (2009/05/26)
(Chemical Equation Presented) NHC-catalyzed direct amidation of aldehydes with nitroso compounds is a powerful method for the synthesis of N-arylhydroxamic acids. A variety of aryl, alkyl, alkenyl, and heterocyclic aldehydes were found to give excellent yields of the corresponding N-arylhydroxamic acids. This chemistry was also extended to the synthesis of chiral N-arylhydroxamic acids by kinetic resolution of α-branched aldehydes, a domino amidation-redox amination reaction of acrolein, and a three-component reaction for the synthesis of N-arylaziridines.
N-HETEROCYCLIC CARBENE (NHC) CATALYZED SYNTHESIS OF HYDROXAMIC ACIDS
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Page/Page column 34, (2008/12/07)
A process for preparing hydroxamic acids is provided. The process comprises reacting an aldehyde with a nitroso compound in the presence of a N-heterocyclic carbene (NHC) catalyst.
A Novel Conversion of N-Aryl-N-methoxyamides into N-Arylhydroxamic Acids Using AlCl3/Thiol System
Kawase, Masami,Kitamura, Takahiro,Shimada, Masahiro,Kikugawa, Yasuo
, p. 887 - 892 (2007/10/02)
Treatment of N-aryl-N-methoxyamides with AlCl3 in EtSH (or Me2S) generates the corresponding N-aryl-N-hydroxyamides in high yields.
