1289221-55-1Relevant academic research and scientific papers
Transition metal-catalyzed carbocyclization of nitrogen and oxygen-tethered 1,n-enynes and diynes: Synthesis of five or six-membered heterocyclic compounds
Zhang, Di-Han,Zhang, Zhen,Shi, Min
, p. 10271 - 10279 (2012/11/07)
Cycloisomerization of 1,n-enynes and diynes is a powerful method in organic synthesis to access heterocyclic compounds and has drawn increasing attention from organic chemists. In this paper, we attempted to summarize our recent results on the transition
Gold(I)-catalyzed cycloisomerization of 1,6-diynes: Synthesis of 2,3-disubstituted 3-pyrroline derivatives
Zhang, Di-Han,Yao, Liang-Feng,Wei, Yin,Shi, Min
, p. 2583 - 2587 (2011/04/27)
A novel synthetic protocol for the preparation of the title compounds has been developed from a gold-catalyzed cycloisomerization of 1,6-diynes containing propargylic ester and arene-yne units. The corresponding nitrogen-containing five-membered heterocyclic compounds have been obtained in moderate to good yields (see scheme; DCE=1,2-dichloroethane, Tf=triflate). A plausible reaction mechanism has been proposed on the basis of deuterium labeling experiments. Copyright
