1289385-11-0Relevant articles and documents
Design and Identification of a GPR40 Full Agonist (SCO-267) Possessing a 2-Carbamoylphenyl Piperidine Moiety
Furukawa, Hideki,Miyamoto, Yasufumi,Hirata, Yasuhiro,Watanabe, Koji,Hitomi, Yuko,Yoshitomi, Yayoi,Aida, Jumpei,Noguchi, Naoyoshi,Takakura, Nobuyuki,Takami, Kazuaki,Miwatashi, Seiji,Hirozane, Yoshihiko,Hamada, Teruki,Ito, Ryo,Ookawara, Mitsugi,Moritoh, Yusuke,Watanabe, Masanori,Maekawa, Tsuyoshi
, p. 10352 - 10379 (2020/10/02)
GPR40/FFAR1 is a G-protein-coupled receptor expressed in pancreatic β-cells and enteroendocrine cells. GPR40 activation stimulates secretions of insulin and incretin, both of which are the pivotal regulators of glycemic control. Therefore, a GPR40 agonist
