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(6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine is a chemical compound characterized by the presence of a chlorine atom, a pyrimidine ring, a methanesulfonyl group, and an isopropylamine group. It is recognized for its potent and selective antagonism of the P2X3 receptor, which is integral to the mechanisms of pain sensation and transmission. (6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine has garnered interest due to its potential therapeutic applications, particularly in the management of chronic pain and other conditions associated with the P2X3 receptor. Its well-defined chemical structure also positions it as a significant asset for advancing research into the role of the P2X3 receptor in pain and various physiological processes, with implications for drug development in pain management and related therapeutic fields.

1289386-49-7

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1289386-49-7 Usage

Uses

Used in Pharmaceutical Research:
(6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine is utilized as a research tool for investigating the function and role of the P2X3 receptor in pain pathways. Its selectivity for this receptor makes it valuable in elucidating the receptor's contribution to pain sensation and transmission.
Used in Pain Management:
In the field of pain management, (6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine is considered as a potential therapeutic agent for the treatment of chronic pain conditions. Its antagonistic action on the P2X3 receptor suggests that it could provide relief by modulating the pain signals transmitted through this receptor.
Used in Drug Development:
(6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine holds promise in the development of new drugs targeting the P2X3 receptor for various therapeutic applications. Its precise interaction with the receptor could lead to the creation of novel medications for treating pain and related disorders.
Used in Neurological Research:
In the context of neurological research, (6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine serves as a chemical probe to explore the intricate relationships between the P2X3 receptor and neurological processes, potentially uncovering new avenues for the treatment of neurological disorders with pain components.
Used in Preclinical Models:
(6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine is applied in preclinical models to assess its efficacy and safety in treating pain and related conditions. Such studies are crucial for advancing the understanding of its potential as a therapeutic agent and for guiding further development towards clinical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1289386-49-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,9,3,8 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1289386-49:
(9*1)+(8*2)+(7*8)+(6*9)+(5*3)+(4*8)+(3*6)+(2*4)+(1*9)=217
217 % 10 = 7
So 1289386-49-7 is a valid CAS Registry Number.

1289386-49-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-chloro-2-methylsulfonyl-N-propan-2-ylpyrimidin-4-amine

1.2 Other means of identification

Product number -
Other names (6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-isopropyl-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:1289386-49-7 SDS

1289386-49-7Upstream product

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