1289448-33-4Relevant academic research and scientific papers
Investigation of alkyne regioselectivity in the Ni-catalyzed benzannulation of cyclobutenones
Stalling, Timo,Harker, Wesley R. R.,Auvinet, Anne-Laure,Cornel, Erik J.,Harrity, Joseph P. A.
supporting information, p. 2701 - 2704 (2015/02/05)
A Ni-catalyzed benzannulation reaction of cyclobutenones and alkynes provides a rapid synthesis of heavily substituted phenols. The regioselectivity of this reaction can be modulated by variation of substituents on the alkyne. Though the incorporation of
COMPOUNDS AND METHODS OF MAKING THE SAME
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Page/Page column 31, (2012/06/16)
The invention provides a process of making an ortho- and/or meta-boronic acid phenol or derivative of such boronic acid comprising: reacting a cyclobutenone with an alkynyl boronic acid or derivative thereof in the presence of a transition metal olefin co
A Nickel-catalyzed benzannulation approach to aromatic boronic esters
Auvinet, Anne-Laure,Harrity, Joseph P. A.
, p. 2769 - 2772 (2011/05/04)
Off and on: A nickel-catalyzed benzannulation of alkynylboronates provides functionalized phenols with high levels of chemo- and regioselectively. While transmetalation of organoboron intermediate to organonickel does not occur during cycloaddition, it is "switched on" by addition of base, thus allowing a one-pot benzannulation and cross-coupling to be realized (see scheme; Pin=pinacolato, Ms=mesyl). Copyright
