1289448-53-8Relevant academic research and scientific papers
Investigation of alkyne regioselectivity in the Ni-catalyzed benzannulation of cyclobutenones
Stalling, Timo,Harker, Wesley R. R.,Auvinet, Anne-Laure,Cornel, Erik J.,Harrity, Joseph P. A.
supporting information, p. 2701 - 2704 (2015/02/05)
A Ni-catalyzed benzannulation reaction of cyclobutenones and alkynes provides a rapid synthesis of heavily substituted phenols. The regioselectivity of this reaction can be modulated by variation of substituents on the alkyne. Though the incorporation of
A Nickel-catalyzed benzannulation approach to aromatic boronic esters
Auvinet, Anne-Laure,Harrity, Joseph P. A.
, p. 2769 - 2772 (2011/05/04)
Off and on: A nickel-catalyzed benzannulation of alkynylboronates provides functionalized phenols with high levels of chemo- and regioselectively. While transmetalation of organoboron intermediate to organonickel does not occur during cycloaddition, it is "switched on" by addition of base, thus allowing a one-pot benzannulation and cross-coupling to be realized (see scheme; Pin=pinacolato, Ms=mesyl). Copyright
