128949-55-3Relevant academic research and scientific papers
Enantioselective Pummerer-type rearrangement by reaction of O-silylated ketene acetal with enantiopure α-substituted sulfoxides
Kita, Yasuyuki,Shibata, Norio,Fukui, Seiji,Bando, Masahiko,Fujita, Shigekazu
, p. 1763 - 1767 (2007/10/03)
Chiral non-racemic α-substituted sulfoxides have been allowed to react with O-silylated ketene acetals in the presence of a catalytic amount of ZnI2 in THF to give chiral non-racemic α-siloxy sulfides in >99% ee. This is the highest enantioselectivity reported to date for the Pummerer reaction.
Studies on the stereoselective methylation of α-sulfinyl carbanions generated from three isomeric pyridylmethyl π-tolyl sulfoxides and benzyl 2-pyridyl sulfoxide
Furukawa,Hosono,Fujihara,Ogawa
, p. 461 - 465 (2007/10/02)
A high stereoselectivity in the methylation of 2-pyridylmethyl p-totyl sulfoxide (2a) with lithium diisopropylamide and iodomethane was observed at low temperature. The chelation of Li+ by both the nitrogen atom in the pyridine ring and the sulfinyl oxygen atom in 2a promotes the stereoselectivity as compared with isomeric sulfoxides.
