1289514-49-3

Upstream product

• 4369-13-5 3,5-bis-(4-fluoro-benzylidene)-1-methyl-piperidin-4-one 
• 109-77-3 malononitrile 
• 920030-35-9 (3E,5E)-1-methyl-3,5-bis(4-fluorobenzylidene)piperidin-4-one 

Relevant academic research and scientific papers

Quinine-catalyzed enantioselective tandem conjugate addition / intramolecular cyclization of malononitrile and 1,4-dien-3-ones

An organocatalytic tandem conjugate addition / intramolecular cyclization of malononitrile and conformationally restricted 1,4-dien-3-ones has been developed. A series of cinchona alkaloids and their derivatives were examined as the catalysts. Quinine was

Organocatalytic conjugate addition of malononitrile to conformationally restricted dienones

Organocatalytic conjugate addition of malononitrile to conformationally restricted dienones has been studied. A series of chiral primary and tertiary amine catalysts were screened. A piperidine-based thiourea-tertiary amine was found to be the efficient c