1289543-33-4Relevant academic research and scientific papers
CeCl37H2O: A versatile and efficient reagent for the synthesis of C-pyrrolyl glycosides
Reddy, Basi V. Subba,Jain, Ruchi,Bhargavi, Kudikyala,Swain, Manisha,Yadav, Jhillu S.
, p. 337 - 341 (2011)
1,3-Diketones and β-oxo esters undergo smooth coupling with d-glucosamine in the presence of 25 mol% CeCl37H2O in water at 80 C to furnish C-pyrrolyl glycosides in good to high yields. The reaction of cyclic diketones such as dimedone with d-glucosamine affords the corresponding 2-(3,4-dihydroxytetrahydrofuran-2-yl)-6,7-dihydro-1H-indol-4(5H)- one derivatives. These dihydroxy derivatives are directly converted into acetates using acetic anhydride and 4-(dimethylamino)pyridine. The use of readily available CeCl37H2O makes this procedure quite simple, convenient and practical. Georg Thieme Verlag Stuttgart New York.
