1289576-24-4

Basic information

• Product Name: C₂₁H₁₆N₄OS
• CAS NO: 1289576-24-4
• Molecular Weight: 372.45
• Mol File: 1289576-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₆N₄OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₆N₄OS(1289576-24-4)
• EPA Substance Registry System: C₂₁H₁₆N₄OS(1289576-24-4)

Safety Data

• Hazardous Substances Data: 1289576-24-4(Hazardous Substances Data)

Upstream product

• 5351-69-9 4-Phenyl-3-thiosemicarbazide 
• 62-53-3 aniline 
• 103-72-0 phenyl isothiocyanate 
• 591-50-4 iodobenzene 
• 28492-94-6 isatin-3-(N⁴-benzylthiosemicarbazone) 

Relevant articles and documents

Isatin-β-thiosemicarbazones as potent herpes simplex virus inhibitors

A series of isatin-β-thiosemicarbazones have been designed and evaluated for antiviral activity against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in a plaque reduction assay. Their cytotoxicity was examined using human rhabdomyosarcoma cells (RD cells). Several derivatives of isatin-β-thiosemicarbazone exhibited significant and selective antiviral activity with low cytotoxicity. It was found that the thiourea group at thiosemicarbazone and the NH functionality at isatin were essential for their antiherpetic activity. The synthesis and structure-activity relationship studies are presented.